The role of D3 sites in disease, however, remains to be established. Genetic centralia pussy swinging of D3 receptor polymorphisms with neuropsychiatric disorders have been proposed.
Alterations in expression of D3 sites may occur in some diseases. Although the study of this receptor is clearly in the early stages, these findings lay the foundation for future investigation.
In this review, dopamine D3 receptor brain localization, cellular aling mechanisms, and associated behavior will be discussed. The potential role of the D3 site in neuropsychiatric disorders and as a therapeutic target is also addressed. This is a preview of subscription content, log in to check access.
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